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The compound showed an in vitro NNMT IC 50 of approximately 1.2 M and did not inhibit related methyltransferases at concentrations tested

Isnt the statement .with no malice aforethought akin to saying I dont wish to be rude, but. Why make a point of such a statement when the irony is that the whole study is designed to cut down on perceived (and not scientifically backed up) excess treatment which served to harm patients and did not, by any stretch of the imagination prevent illness

The reason for pairing them is to support skin remodeling during rapid weight loss, but no controlled trial has tested the combination or shown that effect

Most people dont notice any difference