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It is driven by its superior dosing convenience and sustained therapeutic efficacy
289 Linking ERAD to calcium homeostasis High ER Ca 2+ levels are required for proper ER function, and disruption of Ca 2+ homeostasis promotes the deposition of misfolded proteins within the ER
What are the roles of calorie restriction and diet quality in promoting healthy longevity
They occupy a middle ground between small-molecule compounds and full proteins, which is precisely what makes them useful research tools: peptides are large enough to interact selectively with specific receptors and signaling pathways, yet small enough to synthesize with high structural precision
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