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SIRT: sirtulin
Jensen JK et al
The program, which began in 2024, has enrolled more than 2,050 participants and additional results are anticipated over the next year
The combination is generally well-tolerated, but potential side effects include fatigue, headache, or dizziness from Zofran, alongside semaglutide-related effects like nausea, diarrhea, or reduced appetite
Retatrutide's extended half-life means that missing a single dose by a day or two is unlikely to cause a dramatic loss of drug effect
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