Co-founder & Lead Biochemist - Vitall|Profile Reviewed on 20/10/2025 Next review due 20/10/2026 Review focus: Blood biomarkers, laboratory testing methodology, and biochemical interpretation
Glutathione is the bodys main antioxidant, and, like a firefighter, it helps prevent free radicals from worsening
To verify that GSH per se is not critical for mTORC1 and the ISR signaling, we incubated cells with GSHee, a cell-permeable GSH
Prx5 protects against ferroptosis in bladder cancer, where it is also a potential biomarker [166] , colorectal cancer cells [167] , and cisplatin-induced ferroptosis leading to acute kidney injury [168]
Intestinal permeability occurs when holes develop in the intestinal barrier, often due to damage caused by: Adrenal fatigue Alcohol Capsaicin (in spicy peppers) Dental infections Dysbiosis Enzyme deficiencies Food sensitivities Gluten Gut infections Nonsteroidal anti-inflammatory drugs (NSAIDs) Nutrient depletions Psychological stress Small intestinal bacterial overgrowth (SIBO) Sinus infections Strenuous exercise Stress Surgery or trauma Toxins These holes in the intestinal lining allow for toxins and food particles to leak into the bloodstream, and the body labels these molecules as foreign invaders
