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High-pressure (e.g., greater than 80 to 100 cm H 2 0), long-duration (e.g., greater than 10 minutes) hydrodistension is associated with increased frequency of serious AEs (e.g., bladder rupture, sepsis) without a consistent increase in benefit

Initial fatigue: Some report tiredness during first weeks

For now, consider it a budding field of study rather than an get younger magic bullet

Owing to its unique structure and mode of action, SS-31 demonstrates potential therapeutic value across cardiovascular diseases, neurodegenerative disorders, kidney injury, and myopathies associated with mitochondrial dysfunction 1-6