Therefore, the present post hoc analysis divided subjects based on clinically relevant factors (prior MI or stroke vs no prior MI or stroke and established CVD vs risk factors alone) to allow for exploration of CV outcomes across these CV risk subgroups
I just mentioned a post-diagnosis weight gain of over 10% is associated with worse outcomes, so if that 5% weight loss can be combined with additional lifestyle factors, that gets towards attenuating that weight gain that patients may see and can be meaningful in terms of patients quality of life, how they tolerate their endocrine therapies, how they feel, and their body image
2022 Dec;96:102289 (5) Bassett PA, Abbara A, Goldmeier D, Comninos AN, Dhillo WS
This makes it easier for individuals to stick to healthier eating patterns, thus contributing to weight loss over time
Notably, this trial captured reasons for discontinuation in a more granular way