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Some studies have shown increased levels of advanced glycation end-products (AGEs) in the brains of AD patients, suggesting that AGEs play an important role in activating microglia and A deposition in AD (Byun et al., 2012)

ER: While glutathione keeps the lights on in the mitochondria, its primary job in the ER is quality control. First Visual Evidence: Working with Memorial Sloan Kettering, the team was able to visualize exactly how the SLC33A1 protein binds and moves its cargo across the ER membrane

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Princeton Legacy Library, Rand Corporation research study

Blumer I, Pettus JH, Santos CT