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As a shared therapeutic target for DM and its complications, NRF2 activation holds promise as a novel therapeutic strategy

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The large concentration difference between GSH and GSSG creates a dynamic-range challenge, requiring calibration and dilution procedures that maintain GSSG sensitivity without GSH saturation or carryover

At a time when catalase was the best-known H 2 O 2 -removing enzyme in plants, the paper emphasised the integration of ROS removal with NADPH-producing metabolism

doi: 10.4049/jimmunol.170.1.503 164 HsiehCSMacatoniaSETrippCSWolfSFO'GarraAMurphyKM