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Chronic conditions such as allergic asthma, allergic rhinitis, food allergy, atopic dermatitis, and anaphylaxis impair quality of life and contribute to substantial healthcare expenditures (143)
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10.3389/fnagi.2022.872134 Front
The biphasic response suggests possible mechanisms: lower doses (nanogram range) might work through growth factor upregulation and signaling cascade amplification, while higher doses (microgram range) might involve direct receptor activation or substrate provision for cellular repair
In addition, in a pig model, Lactobacillus reuteri XL0930 in the gut microbiota reduced muscle carnitine levels and promoted fatty acid deposition by downregulating SLC22A5 in muscle tissue [253]
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