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However, since Ozempic has been on the market, some users have reported new or worsening joint pain after starting the medication

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Even in patients who did not lose significant weight, inflammatory markers dropped

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Patients interested in the broader comparison between semaglutide with B12 and tirzepatide with B12 should consider that both benefit from the added vitamin, but the underlying mechanism of tirzepatide (dual receptor activation) provides a different therapeutic profile