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More importantly, the calculation of these descriptors does not account for solution and formulation conditions, which play a very important role in the viscosity of a high-concentration drug product as we have discussed above
PubMed laboratory research record [PMID: 27237818] PubMed record related to this compound for laboratory literature review
doi:10.2174/1570159x1 3666160502153022
This is also in agreement with other studies reporting amplified sartan-induced thermal fluctuations that uncouple the bilayer stacks [304, 305], most likely due to a softening of the membrane as expected from the reduction in the area per lipid
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