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doi: 10.1056/NEJMoa1411892
have previously shown that GSH-dependent glutathione peroxidase 4 (Gpx4) activity is critical for MZB compared to FoB 33
Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL
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Some recommend maintaining the highest tolerated dose to prevent weight regain, while others support gradual reduction with close monitoring and lifestyle changes
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