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Mol Cell Biochem (2021) 476(6):2491501
The classification helps answer the question: "What am I actually taking, and how does it compare to what I read about online?" [Diagram suggestion: Four-quadrant matrix with axes labeled "Receptor target" (pure GLP-1 vs multi-agonist) and "Approval status" (FDA-approved vs compounded), with all medications plotted in their respective quadrants] The pattern we see in FormBlends refill data: patients often start on compounded semaglutide (Tier 4), then switch to brand-name Wegovy (Tier 1) when insurance coverage becomes available, then switch to tirzepatide (Tier 3) if weight loss plateaus
They protect skin cells
