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As expected, the molecular metal complex Ru(II)-OH was quickly cleared from the blood stream with a blood circulation half-life time of 0.28 h
Tellides G, Pober JS
JY and FQ provided administrative support
The first bioreversible prodrug of metformin with improved lipophilicity and enhanced intestinal absorption
Our preliminary interpretation is that replacement of Tyr110 indeed affects the interaction with GSH but, as compared to K105A/Y, does not drastically alter the ratio between the steady-state concentrations of the deprotonated and glutathionylated enzyme species E and F, respectively
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