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SURMOUNT-1 (Jastreboff 2022, NEJM) showed up to 20.9 percent with tirzepatide at 72 weeks

Multi-indication label expansion: Semaglutide approved across obesity, cardiovascular risk reduction, MASH, and sleep apnea creates a total addressable patient population of approximately 640 million globally nearly four times the obesity-only base adding new prescriber populations including cardiologists, hepatologists, and sleep medicine specialists