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2.2.2 ERK1/2-HDAC6 signaling pathway The GLP-1R-ERK1/2-HDAC6 signaling pathway complements the mitophagy pathway by modulating oxidative stress and autophagy

Tian et al

Participants showed improvements in multiple aging markers, including oxidative stress, mitochondrial function, muscle strength, and even walking speed

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The Lancet Diabetes & Endocrinology , 12(3), 201-213