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Retatrutide achieved up to 24.2% body weight reduction in 48 weeks in Phase 2, and the recently completed Phase 3 TRIUMPH-4 trial pushed that number to an unprecedented 28.7% at 68 weeks
doi: 10.3389/fphar.2020.600175 Received 29 August 2020 Accepted 18 December 2020 Published 04 March 2021 Volume 11 - 2020 Edited by Predrag Sikiric, University of Zagreb, Croatia Reviewed by Na Li, Shanghai Jiao Tong University, China Gabor Varga, Semmelweis University, Hungary Updates Copyright 2021 Zhou, Lin, Cheng, Zhuo, Li, Xu, Zhao and Yang
Rapamycin was shown to have multiple actions including anti-proliferative and immunosuppressive effects through modulation of mTOR and FK506-binding protein (Li et al
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