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Autophagy 19(10):26212638 Conrad M, Proneth B (2020) Selenium: tracing another essential element of ferroptotic cell death
In the proteinprotein interaction (PPI) network, we obtained that Nrf2 regulates ferroptosis primarily by directly affecting the synthesis and function of GPX4 and the peroxisome proliferator-activated receptor gamma (PPAR) pathway, and we hypothesize that the regulation of intracellular iron concentration by Nrf2 is mainly through the Nrf2HO-1 axis
Interestingly, the majority of the 103 downregulated genes after 4 h of aloxistatin treatment were also found to be downregulated after 24 h (Fig
Often, liver enzymes in blood tests, such as ALT and AST, can indicate damage before physical symptoms arise
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