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The thyroid gland is just one of the glands in this system that includes the pituitary gland, the thymus, the adrenal glands, the pancreas, and many more
Importantly, these arent just appetite effects the animals specifically reduce alcohol-seeking behavior even when food is held constant, suggesting an independent mechanism acting on reward circuitry
Its mostly a cosmetic issue, but permanent changes can occur, so it factors into the risk-benefit consideration for long-term frequent use
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