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Studies treating mild to moderate B12 deficiency in older people have failed to provide cognitive benefits: A clinical trial from the Netherlands measured the cognitive response to B12 supplements in people 70 years old with mild B12 deficiency and MMA levels 320 nmol/l (average: ~450 nmol/l)

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Recommended Testing Schedule Heres a suggested testing plan for B12 treatment: First test B12 levels before starting treatment Check again after the first dose (usually 1-3 months later) Test every 3-6 months while taking maintenance doses Test more often if you have trouble absorbing B12 or other health issues Interpreting B12 Levels During Treatment When looking at B12 levels, doctors must think about a few things

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Troubleshooting: Do not shake the vial