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Individuals with active cancer or a history of malignancy should avoid the peptide unless under medical supervision, as effects on tumor growth have not been adequately studied

Temperature proves the dominant factor affecting degradation rates - every 10C increase doubles degradation speed, making refrigeration at 2-8C essential for all reconstituted solutions and beneficial for extending powder shelf life beyond basic 12-18 month refrigerated baseline

Kanbay M, Yayci E, Genc C, Copur S, Aktas O, Sarafidis P, Covic A, Ortiz A, Laffin LJ

Arteaga-Henrquez G, Gisbert L, Ramos-Quiroga JA

This is why we often recommend to our members that they ask their doctor to put in writing their reasons for deviating from the guidelines