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Metformin should not be used in patients with metabolic acidosis
Zepbound contains the same active ingredient, tirzepatide, as another medication, Mounjaro, which is also made by Lilly and is FDA-approved to treat Type 2 diabetes
Insurance coverage and cost Insurance coverage for Mounjaro will vary by plan
The SURMOUNT-1 trial showed meaningful weight loss at every dose level, with 5mg producing an average 15% body weight reduction over 72 weeks
(F) Uncoupling protein 1 (UCP1) and (G) mitochondrial oxidative phosphorylation (OXPHOS) complex proteins in brown adipose tissue (BAT), assessed by immunoblotting, with quantification normalized to the high-fat diet (HFD)+Veh group
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