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doi:10.1016/s0076-6879(02)45028-8
The FDA has issued warnings about compounded GLP-1s because some contain salt forms (e.g., semaglutide sodium or acetate) that differ from the approved drug, and quality control can vary across compounding pharmacies
Recent findings also revealed concerns with the loss of skeletal muscle mass when taking GLP-1RAs with some studies reporting up to 50% of weight loss being due to decreases in muscle mass
Endotoxin exposure can also contribute to the development of chronic diseases such as metabolic syndrome, diabetes, and cardiovascular disease
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