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Summary: Weight gain during retatrutide treatment is most commonly caused by fluid retention, dose titration phases, metabolic adaptation, dietary habits, or underlying health conditions rather than the drug failing to work

If you take oral contraceptives, blood pressure medications, or other drugs that require consistent absorption, discuss the implications of medication cycling with your prescribing physician

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Gastrointestinal Side Effects and Overload Both Ozempic and berberine are known for causing gastrointestinal (GI) side effects