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Another observation from studies on murine models exposed to catabolic agents revealed a reduction in the excretion of N-methylhistidine, a marker of muscle protein degradation, which was notably more pronounced with IGF-1 LR3potentially three times greater than with IGF-I

Gmunder H, Droge W

Many practitioners also recommend not washing B12 down with strong coffee or energy drinks, especially if you are sensitive to caffeine or prone to stomach upset. Can You Take Vitamin B12 with Other Supplements

Schneider CA, Figueroa Velez DX, Azevedo R, Hoover EM, Tran CJ, Lo C, et al