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The answer is yesthey work synergistically for better results

As a major contributor to global mortality and disability, NDDs are associated with diverse pathological mechanisms, including neuroinflammation, oxidative stress, mitochondrial dysfunction, synaptic impairment, and neuronal loss (Lv et al., 2025)

Niacin cures systemic NAD+ deficiency and improves muscle performance in adult-onset mitochondrial myopathy

The studys authors found that using the antioxidant N-acetyl-cysteine (NAC) reduced ROS and DNA damage

The liver can only process one standard drink per hour, so if we drink too much or too quickly, were asking for trouble