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Low protein intake due to reduced appetite may also contribute to muscle loss and increased risk for sarcopenia especially among those with older age, sedentary behaviour and a lack of resistance/strength training

GLP-1 agonism: Reduces appetite, slows gastric emptying, promotes satiety GIP agonism: Enhances insulin secretion, may reduce GLP-1-related nausea Glucagon agonism: Increases hepatic glucose output control, drives thermogenesis and energy expenditure Phase 2 clinical trial data published in 2023 showed subjects lost an average of 24.2% of body weight over 48 weeks making it arguably the most potent weight-loss compound currently known

Compounded medications are prescription products prepared by licensed pharmacies based on individual prescriptions

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The patient had continued to exercise daily for 1 hour with familial support