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Implication: If you or your family have a history of MTC or multiple endocrine neoplasia type 2, retatrutide is not recommended
Practical indicators include soaking through sanitary protection hourly, passing clots larger than a 50p coin, or bleeding that lasts longer than seven days
ACKNOWLEDGMENTS The authors thank Alison Sherwin, PhD, from Edanz ( for editing a draft of the manuscript
This drug can also lower the risk of cardiovascular disease
Wegovy evidence in prediabetes STEP 10: the dedicated prediabetes trial STEP 10 was a 52-week randomised, double-blind, placebo-controlled trial in 207 people with obesity and prediabetes, conducted across Canada, Denmark, Finland, Spain, and the UK and led by Professor Barbara McGowan at Guys and St Thomas NHS Foundation Trust
