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Furthermore, we examined whether linagliptin affected cell function, and found that linagliptin significantly up-regulated the relative production of GLP-1 vs glucagon in cells of both non-diabetic and diabetic human islets, which would be beneficial for restoring normoglycemia in diabetes treatment
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10.1038/nature01039 94 WangX.EllenbeckerM.HickeyB.DayN
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