You are planning pregnancy GLP-1 medications are not approved for use during pregnancy
Compounded semaglutide: Prepared by specialty pharmacies and not FDA-approved, but often significantly cheaper
The main mechanism of action of these GLP-1RA is the stimulation of the GLP-1R that triggers the activation of several metabolic pathways involved in insulin secretion, lipid metabolism, energy expenditure, pro-survival and anti-apoptotic cellular signaling, and oxidative stress prevention, in several tissues like the pancreas, central nervous system, heart, muscle, kidneys, gut, among others (15)
Hydration Heroics : We cant emphasize enough the importance of drinking plenty of water throughout the day to combat dehydration and constipation related to GLP-1
May-Jun 2016;82(3):269-74