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Of the 2006 isolates, 1895 (94.5%) harbored at least one ESBL gene: bla CTX-M in 1821 (96.1%), bla SHV in 36 (1.9%), and both in 38 (2.0%) of ESBL-positive isolates
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Regulatory and Ethical Context The FDA has approved recombinant human IGF-1 only as mecasermin (Increlex) for the narrow indication of severe primary IGF-1 deficiency or GH-gene deletion with neutralising antibodies to GH, in children [15]
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