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In a 2011 study by Wise and colleagues of 115 positively identified TMAU subjects, [7] after a choline challenge load test (intentionally ingesting a TMA precursor), only 10% expressed a smell at a social distance
You are comfortable with a somewhat longer titration (20 weeks to 15 mg) in exchange for better efficacy
Two phase-3 trials enrolled 404 and 412 participants respectively
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