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At the 15 mg dose, 91% achieved at least 5% weight loss and 57% achieved at least 20%

Eligible participants had the New York Heart Association (NYHA) functional classes II to IV, a six-minute walking distance (6MWD) of 100 m, and a minimum of increased filling pressure, increased N-terminal pro-brain natriuretic peptide (NT-proBNP) levels with structural echocardiographic irregularities, or a previous history of heart failure-related hospital admission in the prior year with current diuretic therapy

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The legal basis was straightforward