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References Beard, T., Leslie, J., & Nemeth, J

Other documented adverse effects include decreased appetite (which contributes to the therapeutic effect), fatigue, injection site reactions, dizziness, and modest increases in heart rate (typically 2-4 beats per minute)

doi: 10.14283/jpad.2021.14 17 TramutolaAArenaACiniCButterfieldDABaroneE

The local mechanisms of these effects are still under investigation, but GLP-1R co-expresses with proteins known to play an important role in appetite, such as prolactin-releasing peptide and tyrosine hydroxylase [42, 43]