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B12 plays a major role in many key processes, including cell formation, brain and nerve function, energy production, and healthy cognition
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Notably, ergothioneine emerged as the plasma metabolite most strongly linked to a decreased risk of coronary disease (p=0.01), cardiovascular mortality (p=0.002), and overall mortality (p=0.0004)
Ratio predictions for are summarized based on this logic
Key conjugation reactions include: glutathione S-transferase (GST) conjugation, glucuronidation (UGT), sulfation (SULT), methylation (COMT, TPMT), acetylation (NAT), and amino acid conjugation (glycine, taurine)
