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21 August 2020 [Initial approval 4 January 2018]
It is a man-made peptide developed from melanotan 2 through targeted modifications
The two-year data demonstrates that the body does not develop tolerance, the weight does not inevitably rebound while on treatment, and the metabolic improvements persist over the long term
Retatrutide is the first triple agonist (GLP-1, GIP, glucagon) to reach Phase 3 clinical trials for obesity
Ji, Y., Gao, Y., Chen, H., Yin, Y
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