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L-carnitine side effects are generally mild but may include: Nausea, vomiting, or abdominal cramps Diarrhoea or heartburn A 'fishy' body odour (due to trimethylamine production by gut bacteria) Rarely, restlessness or sleep disturbances High doses of L-carnitine (above 3g daily) have been associated with increased seizure frequency in individuals with seizure disorders
No randomized controlled human trials have been conducted
Key takeaways Contrave (bupropion and naltrexone) is an oral medication
Third, residual confounding from unmeasured factors such as smoking status, alcohol intake, family history of cancer, and dietary patterns may have influenced the observed associations but could not be adjusted for in this aggregate-level analysis
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