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The researchers proposed that the compounds effects on muscle function operate through boosting NAD+ levels by inhibiting NNMTs consumption of nicotinamide, more substrate is available for NAD+ synthesis via the salvage pathway, supporting mitochondrial function and energy metabolism in aged skeletal muscle

Kil HJ et al

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis

The result: firmer, more elastic skin, faster regeneration after injuries and treatments, and visible improvement in the condition of hair and tissues

The study included a 26-week treatment period including up to six weeks of dose escalation, followed by a 6-week post-treatment follow-up, extending to week 32