In the STEP 1 clinical trial, around 44% of people at the 2.4 mg dose reported feeling sick most often when they first started or moved up to a higher dose
[44]Jozefczak M, Remans T, et al
In: Proceedings of ESA annual meeting on electrostatics, vol 3, pp 16 Da Silva AB, Arjmand M, Sundararaj U, Bretas RES (2014) Novel composites of copper nanowire/PVDF with superior dielectric properties
An increase in the Akkermansia spp population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice (in Eng)
But the effectiveness can vary based on individual skin biology, pigmentation levels, and overall health