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doi: 10.1038/s41401-024-01359-9 66 MarchiSPatergnaniSMissiroliSMorcianoGRimessiAWieckowskiMRet al
His colleague Shin-ichiro Imai, a professor of developmental biology at the Washington University School of Medicine who first met Sinclair in Guarentes lab, says Sinclair had a keen eye for capturing novel concepts and, based on that foundation, building new lines of research faster than anyone else. At the time, aging research, once considered a fringe science, was still in its infancy, but Sinclair was determined to propel it to legitimacy
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The peptide's immunomodulatory effects include enhancement of T-lymphocyte proliferation in the thymus and increased production of interferon gamma, supporting immune system resilience particularly in aged organisms
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing
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