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In conclusion, understanding the role and stability of L-glutamine in cell culture is crucial for optimizing cell growth and experimental results
Strategies that deplete GSH, such as using inhibitors like BSO which is inhibitor of -glutamylcysteine synthetase (-GCS) , the rate-limiting enzyme in glutathione (GSH) synthesis or by combining prodrug activation with GSH depletion in nanosystems, have shown promise in overcoming MDR and improving chemotherapy effectiveness [72]
Circadian control of the NAD + salvage pathway by CLOCK-SIRT1
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