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1970s: Global health initiatives, including WHO programs, addressed B12 deficiency in developing regions, reducing anemia rates by 10-15% in Africa and Asia through fortified foods

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20 In 2017, Paul and Brady came to similar conclusions that all four forms appear to be effective, although they point out research that shows that tissue retention of cyano-B12 is lower and urinary excretion higher than that of the other forms, although this statement is based on a review from 1965