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You have a ligand, you have a receptor, and the experiments follow: binding assays, competition curves, functional readouts through a known G protein, receptor-expressing cell lines, selective antagonist controls
doi: 10.1016/S0891-5849(00)00280-X 58 CoxP
Potential metabolic effects of allulose (requiring further research): Modest reduction in postprandial glucose levels Possible stimulation of endogenous GLP-1 secretion Potential improvement in insulin sensitivity Reduction in overall caloric intake when substituted for sugar Patients should discuss any dietary modifications with their healthcare provider, particularly when managing diabetes or taking glucose-lowering medications
Consult your physician for more information
H.PolakL.LinM.LayK.ZhengD.FuchsE
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