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The theory of the origin of sleep which has gained the widest credence is the one that attributes it to anemia of the brain The idea behind this supposition has been that, as the day draws to an end, the circulatory mechanism becomes fatigued, the vasomotor center exhausted, the tone of the blood vessels deficient, and the energy of the heart diminished, and thus is the circulation to the cerebral arteries lessened. NATURE, May 5th, 1898
Focal cortical dysplasia type II (malformations of cortical development) aberrantly expresses apoptotic proteins
Therefore, GPX8 not only participates in the folding of proteins in the endoplasmic reticulum, exerts the role of oxidative stress, but also participates in the regulation of Ca 2+ in the endoplasmic reticulum
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