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Additionally, foods high in vitamin C (citrus fruits, strawberries) and selenium (Brazil nuts, sunflower seeds) further support glutathione synthesis and function
LA is a unique antioxidant that is not only effective in affording protection against oxidative stress but also plays an essential role in the metabolic processes of all living organisms 36
The recruitment of AKT1 to the plasma membrane or intracellular membrane through binding of its PH (pleckstrin homology) domain to PIP3 (phosphatidylinositol 3,4,5-trisphosphate) is a prerequisite for AKT1 phosphorylation at threonine (T) 308 by PDK1 and at serine (S) 473 by Rictor-mTOR complex (mTORC2) 26,27
The underlying mechanism may be related to GSH metabolism (163), abnormal iron metabolism (164), lipid peroxidation (165) and mitochondrial dysfunction (166)
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