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Conclusions In the STEP-HFpEF trial, semaglutide improved symptoms, physical limitations, and exercise function, and reduced inflammation, NT-proBNP, and body weight in patients with the obesity phenotype of HFpEF across the range of EF

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These recommendations are not medical advice and don't substitute for guidance from your prescribing physician or a registered dietitian

These symptoms may indicate serious complications such as acute pancreatitis, bowel obstruction, or severe gallbladder disease requiring urgent intervention

Liver Fat (MASLD) A Phase 2 trial showed retatrutide reduced liver fat by 82%