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This mechanism relies on intact pituitary and hypothalamic function, making efficacy dependent on baseline hormonal reserve and individual receptor sensitivity

The biomarker discovery phase data of participants 1 and 2 overlaps with ambulatory data used in our previous report 21

Include activities like walking, cycling, or swimming to get your heart rate up and burn calories

Patients with RA often experience cardiovascular comorbidities, and certain GLP-1 medications have demonstrated cardiovascular benefits in high-risk populations

STEP-1 and SURMOUNT-4, How Long Results Typically Last The STEP-1 trial extension provides a stark example of what happens after treatment stops