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Whether the amount found in energy drinks (or in this case, 5-Hour Energy shots, not in Monster) can produce this effect is debatable
When folic acid builds up in the body, it can actually slow down the methylation cycle and even interfere with HNMT (histamine N-methyltransferase) , the enzyme that helps break down histamine
Cromie GA, Tan Z, Hays M, Sirr A, Jeffery EW, Dudley AM (2017) Transcriptional profiling of biofilm regulators identified by an overexpression screen in Saccharomyces cerevisiae
Some healthcare providers might recommend additional monitoring if the medication is being used off-label, such as more frequent check-ins or additional lab tests to ensure safety and effectiveness
Extra-facial melasma: clinical, histopathological, and immunohistochemical case-control study
