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The decoupled catalytic kinetics and substrate adsorption profiles reveal the bifunctional merits of the fusion architecture, including prolonged operational stability through strengthened substrate binding, and the attenuated product inhibition achieved via spatial segregation of hydrolytic domains

[30] Vendrell-Flotats M, Arcarons N, Barau E, Lpez-Bjar M, Mogas T

Topical/cosmetic GHK-Cu Human studies on GHK-Cu have primarily focused on the topical route of administration

They are often designed to improve the bioavailability of active drugs by increasing their amount in target cells and reducing off-target effects

Proc Am Assoc Cancer Res 44:623, 2003