SULT1A1 also takes part in transformation of hydroxymethyl polycyclic aromatic hydrocarbons, hydroxyderivatives of arylamines, allylic alcohols and heterocyclic amines to their reactive intermediates which are able to bind to nucleophilic structures such as DNA and consequently act as mutagens and carcinogens (Glatt et al., 2001)
What are KLOW side effects
Ferdous Z, Elzaki O, Beegam S, Zaaba NE, Tariq S, Adeghate E, et al
The International Journal of Neuropsychopharmacology, 28, pyaf067
It is suggested that these side effects are due to mitochondrial dysfunction, decreased antioxidant activity, and induction of inflammatory and apoptotic mediators